CORDOMA DEL CLIVUS PDF

CORDOMA DEL CLIVUS PDF

con el diagnóstico histopatológico de cordoma de la base del cráneo .. magnética cerebral, corte sagital, secuencia T1, cordoma del clivus. Resección endoscópica de cordoma del clivus. Descripción de un chordoma; clivus; endoscopic resection; malignant tumor. RESUMEN. Download Citation on ResearchGate | On Dec 19, , Ines Gamboa and others published Resección endoscópica de cordoma del clivus. Descripción de un.

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This year-old woman was healthy until she suffered an episode of dizziness, ataxia, corxoma right hearing difficulty and right facial numbness. The remnant tumor volume was 8. It is of interest that the MR image in our case failed to delineate the right-sided disc herniation. MRI is, however, limited in its ability to evaluate calcification and the precise involvement of skull base osteolysis less well than CT, especially for skull base foramina.

Postoperative brain CT demonstrates no definite contrast enhancing mass in right cerebellopontine angle region and no bony destruction.

Views Read Edit View history. Primary intradural pontocerebellar chordoma metastasizing in the subarachnoid spinal canal.

Intradural retroclival chordoma without bone involvement: Radiological investigations included magnetic resonance MR imaging with gadolinium enhancement of the lumbar region and an iopamidol myelogram with computerized tomography CT of the lower four lumbar vertebrae. Cerebrospinal fluid fistula secondary to ecchordosis physaliphora. Since chordomas arise in bone, they are usually extradural and result in local bone destruction.

Chordoma – Wikipedia

She underwent retromastoid suboccipital craniotomy to resect the tumor mass and adjuvant gamma knife radiosurgery for remnant tumor at 1 month after operation. Find articles by Seung Jin Noh.

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By using this site, you agree to the Terms of Use and Privacy Policy. Additionally, it represents an example of intraspinal extraosseous chordoma, a lesion not previously described. There are no drugs currently approved to treat chordoma, however a clinical trial conducted in Italy using the PDGFR inhibitor Imatinib demonstrated a modest response in some chordoma patients. There are three histological variants of chordoma: Photomicrographs of the tumor specimen.

Such tumors often showed extraosseous extensions that were out of proportion to the degree of osseous involvement and were most often anterior and lateral but did involve the posterior spinal area. The patient was not aware of progressive neurological loss. From Wikipedia, the free encyclopedia. Operation Under the impression of acoustic schwannoma, the patient underwent operation. A small number of families have been reported in which multiple relatives have been affected by chordoma.

Surgical Implications The tumor in our patient lent itself to complete surgical removal. The patient made an uneventful postoperative recovery and was ambulating in a cast brace.

Extraosseous spinal chordoma

Typically the mass projects posteriorly at midline, indenting the pons; this characteristic appearance has been termed the so-called thumb sign. Histological subtype also has a substantial impact on prognosis with chondroid chordoma having the codroma prognosis and dedifferentiated chordoma the worst prognosis; the more common conventional chordoma having intermediate prognosis 14, These foci were micro- rather than macroscopic, were entirely intraosseous, coivus bore no physical resemblance to ecchordosis physaliphora occurring in the cranial region.

Postoperative course The patient complained dizziness, but other symptoms, such as ataxia, right facial numbness without paralysis, right hearing disturbance, were much more improved. Preoperative MR images presenting the intradural retroclival tumor with growing into right cavernous sinus and Meckel’s cave.

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Notochordal rests in the true vertebrae are rare 2 and are primarily located centrally or posteriorly within vertebral bodies. Immunohistochemical analysis showed the positive expression for cytokeratin, epithelial membrane antigen, vimentin and S protein Fig.

The MR appearance of our patient’s tumor was dissimilar to that of true vertebral chordomas because of its extraosseous location. Extent of tumour and contrast enhancement: On initial evaluation, the patient had ataxic gait. In a series of spinal chordomas reported by Sundaresan, et al. In contrast to sacrococcygeal tumours, there is no recognised gender difference. It can be seen that many are from the pre-MRI era, and many do not provide histological or immuno-cytochemical evidence, raising the possibility that some may clibus be entirely extraosseous and some may be not actually be chordoma.

MRI and CT scan have complementary roles in tumor evaluation. Based on our morphological and cel studies, we propose that the tumor presented in this report, a bona fide intraspinal extraosseous extradural chordoma, had its origin in an ectopic notochordal remnant.

CT evaluation is needed to assess the degree of bone involvement and to detect patterns of calcification within the lesion.