Cardiobacterium hominis is a slow-growing, fastidious, capnophilic, Gram- negative bacillus represented by the “C” in HACEK, an acronym for. Cardiobacterium hominis is a member of the HACEK group (Haemophilus paraphrophilus, Haemophilus parainfluenzae, Aggregatibacter. Cardiobacterium hominis, a microaerophilic, pleomorphic gram-negative bacillus , is one of the AACEK organisms. C. hominis is a component of the normal flora.

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Two holes were observed in the aortic valve noted to be quadricuspidwhich was also replaced. At this time she developed a skin rash and was changed to intravenous ciprofloxacin mg 12 hourly, before undergoing aortic valve replacement for progressive heart failure Medicine Baltimore ; Susceptibility testing of C.

Two cases and a review of the literature”. Cardiobacterium hominis endocarditis in a patient with a hypersensitivity reaction to penicillin.

Eur J Clin Microbiol ; 2: Intracranial mycotic aneurysm in a patient with endocarditis caused by Cardiobacterium hominis. Slotnik, using a labeled, hyperimmune, rabbit antiserum and selective culture, was able to detect C.

Recently, two isolates with beta-lactamase production have been reported [ 2426 ].

Cardiobacterium hominis – Wikipedia

S Afr Med J. Am J Med Sci.

Am J Med ; Mueller et al 9 published a case report of a patient with C hominis endocarditis who presented with sudden onset of sharp right calf pain and had a pulseless right foot on examination due to embolic occlusion of the right popliteal artery. Both peak and trough sera were rapidly bactericidal while the patient received ciprofloxacin. Further support for the diagnosis of C. Description of two patients and characterization of the organism”.


Get free access to newly published articles Create a personal account or sign in to: South Med J ; Table 1 summarizes representative susceptibilities of several strains to a range of antibiotics Bourbeau, PhD ; et al Robert E.

Use of corticosteroids in glomerulonephritis related to infective endocarditis: However, because of reports of beta-lactamase-producing C.

Purchase access Subscribe now. C hominis is a pathogen of relatively low virulence 1 ; as such, patients typically present with a picture of subacute endocarditis, often feeling unwell for a period ranging from weeks to months before a diagnosis is reached 1 – Cardiobacterium hominis in genitourinary specimens.

Can Med Assoc J ; Can Assoc Radiol J ; Small glistening opaque colonies usually become apparent after 2 or 3 days, but occasionally take up to 2 weeks. Table 4 Treatment of C.

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Cardiobacterium hominis is a Gram-negative bacillus rod-shaped bacterium commonly grouped with other bacteria into the HACEK group. Eur J Clin Microbiol. Molecular methods of diagnosing this pathogen have recently been reported and may provide an alternative method of diagnosis in the future.

Author manuscript; available in PMC Mar Am Surg ; Cardiobacterium hominisalong with three Haemophilus species Haemophilus parainfluenzaeHaemophilus aphrophilusand Haemophilus paraphrophilusActinobacillus actinomycetemcomitansEikenella corrodensand Kingella species, is a member of the HACEK group of endocarditis-causing gram-negative bacteria.


This case demonstrates the usefulness of both the Steiner stain and broad-range direct molecular amplification as supplemental diagnostic tools in identification of otherwise unexplained infections. Infective endocarditis caused by uncommon bacteria. Detton E, Glikmanas M.

Cardiobacterium hominis endocarditis: two cases and a review of the literature

However, it may also rarely cause endocarditisan infection of the heart valves. Salmonella enterica Typhoid feverParatyphoid feverSalmonellosis. Jolie A, Gnann JW.

Clin Microbiol Infect ; S Afr Med J ; The references cited in all of the case reports included in the present review were examined for additional cases not indexed on MEDLINE. Weiner M, Werthamer S.

Embolization from a valvular vegetation was the presumed cause of these symptoms Two of four patients reported in received tetracycline and chloramphenicol as a part of their therapy. Treatment and susceptibility Treatment was detailed for 58 of the 61 patients, all of whom received a penicillin or cephalosporin sometime during the course of therapy. Antibiotic treatment regimens were recorded, and mortality was noted for each case. C hominis was first isolated from patients with endocarditis in There are very few published data on the bactericidal activity of antibiotics for C.